Martin J. Donnelly

The paper provides genomic resources for malaria vector surveillance in Southeast Asia, revealing population structure and resistance regions in Anopheles dirus.

This study uses genomic data to analyze evolutionary dynamics of Anopheles gambiae under different insecticidal tools, revealing distinct resistance mechanisms and allele frequency shifts.

The paper identifies and characterizes genomic regions under positive selection in malaria vectors using whole-genome sequencing data from 4,306 mosquitoes across twenty-one countries.

In Tororo, Uganda, An. funestus tolerated clothianidin-sprayed walls better than An. gambiae yet was killed on pirimiphos-methyl walls up to 7 months post-spray, implicating it in the malaria resurgence.

This paper uses genomic surveillance in a cluster randomized trial to detect insecticide resistance variants in Ugandan Anopheles funestus and An. gambiae s.l., showing differential population responses to pyrethroid and PBO interventions.

This study uses whole-genome sequencing of Anopheles gambiae s.l. mosquitoes to uncover fine-scale population structure and insecticide resistance mechanisms in central Ghana.

This study traces the origin and spread of Anopheles stephensi in Africa using genomic data and identifies insecticide resistance genes from Asia.

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

The paper investigates insecticide resistance and population structure in Anopheles gambiae from southern DRC, finding high resistance and genetic differentiation between populations.

The paper identifies cis-regulated genes and cis-regulatory modules in Anopheles gambiae associated with insecticide resistance using allele-specific expression and machine learning.

This study identifies a duplicated esterase locus associated with pirimiphos-methyl resistance in Anopheles gambiae through population genomic analysis.

This study examines migration patterns among malaria vector species using genomic data, finding variation in genetic differentiation and migration rates across regions and species.

This study identifies copy number variants (CNVs) as key drivers of insecticide resistance in Anopheles arabiensis, revealing new gene clusters and resistance mechanisms to deltamethrin and pirimiphos-methyl.

The paper analyzes DNA and infection profiles from 100-year-old mosquitoes to determine their genetic profiles and Plasmodium infection status.

RNA-Seq-Pop is a Snakemake workflow for RNA-Seq analysis that identifies pyrethroid resistance mechanisms in Anopheles gambiae by analyzing genetic diversity and differential expression.

This study identifies novel genetic loci associated with resistance to pyrethroid and organophosphate insecticides in Anopheles gambiae s.l. through genome-wide association analyses.

AgamPrimer designs primers and probes for Anopheles gambiae using genomic variation data to avoid amplification issues caused by genetic diversity.

The paper develops a Bayesian spatiotemporal model to analyze the spread of genetic mutations conferring insecticide resistance in malaria vectors, revealing geographic and temporal patterns of resistance.

This study functionally validates the L1014F kdr mutation's role in pyrethroid resistance in Anopheles gambiae and shows its interaction with detoxification enzymes.

This study identifies novel genetic variants and haplotypes associated with pyrethroid resistance in malaria vectors, revealing complex resistance mechanisms and geographical spread.

The paper identifies a resistance mechanism to pirimiphos-methyl in Anopheles mosquitoes through duplication and introgression of the Ace1 locus, showing its spread in West Africa.

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.

This study identifies genes associated with bendiocarb resistance in Ugandan Culex quinquefasciatus mosquitoes through transcriptomic analysis.

The paper develops and validates an ETAS-PCR assay for detecting tri-allelic Vgsc-L1014F mutations in Culex quinquefasciatus, showing high correlation with established methods.

This study presents the first genomes of trombidid mites, revealing novel allergens and laterally transferred genes involved in secondary metabolism.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.