Cancer BiologybioRxivPreprint
Loss of Gαq reshapes key fibroblast traits and drives matrix remodeling and aggressive progression of oral cancer tumors
Inmaculada Navarro‐Lérida, Raquel Huertas‐Lárez, Gemma Paredes-Garcia…·Catalina Ribas
This study shows that loss of Gαq in fibroblasts promotes aggressive oral cancer progression by altering ECM remodeling, exosome secretion, and tumor cell migration.