Author

Juana Maria Garcia-Pedrero

Universidad de OviedoORCID 0000-0002-5891-9488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Juan Pablo RodrigoiD· 3 shared Saúl Álvarez–TeijeiroiD· 3 shared Beatriz de Luxán‐DelgadoiD· 2 shared Catalina RibasiD· 2 shared Francisco Hermida‐PradoiD· 2 shared Inmaculada Navarro‐LéridaiD· 2 shared Llara Prieto-FernándeziD· 2 shared Mónica Álvarez‐FernándeziD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Juan Pablo RodrigoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NGFR-driven suppression of antigen presentation limits CD8+ T cell immunity and response to checkpoint blockade

Juan García-Agulló, Vanesa Santos, Blanca Majem, Mariola Munárriz-Paños, Laura Serrano-Ron, Maria Calvo de Mora, Sara Sánchez‐Redondo, Daniel Achuela, Teresa Aceña-Gonzalo, Inés Sentís, Gloria Pascual, Carmen Blanco‐Aparicio, Fátima Al‐Shahrour, Eduardo J. Caleiras, Isabel Peset, , Héctor Peinado

This study identifies NGFR as a regulator of immune evasion in HNSCC, showing that its inhibition enhances antigen presentation and CD8+ T cell response to checkpoint blockade.

bioRxiv · Aug 25, 2026 · PreprintCancer Biology

Functional proteomics identifies targetable cancer-associated fibroblast programs in head and neck cancer

Llara Prieto-Fernández, Ana Martínez‐Carrillo, Lucas de Villalaín, Alejandra García‐Torre, Beatriz de Luxán‐Delgado, Francisco Hermida‐Prado, Inmaculada Navarro‐Lérida, Catalina Ribas, Ramón García‐Escudero, Juan Pablo Rodrigo, Juan Carlos de Vicente, Tania Rodríguez‐Santamarta, Juana Maria Garcia-Pedrero, Saúl Álvarez–Teijeiro

The paper identifies functionally distinct and pharmacologically targetable cancer-associated fibroblast (CAF) programs in head and neck cancer using proteomic and functional assays.

bioRxiv · Aug 21, 2026 · PreprintCancer Biology

PATIENT-DERIVED ORGANOIDS CAPTURE HISTOLOGICAL, MOLECULAR AND THERAPEUTIC HETEROGENEITY IN PHARYNGEAL AND LARYNGEAL SQUAMOUS CELL CARCINOMAS

Miguel Álvarez-González, Esperanza Pozo-Agundo, Beatriz de Luxán‐Delgado, Helena Codina‐Martínez, Borja Gallego, María Otero‐Rosales, Israel Rivera-García, Andrea Blazquez, Mar Rodríguez-Santamaría, Daniela Corte-Torres, Saúl Álvarez–Teijeiro, Sonia Blanco Parajón, Fernando Lopez, Francisco Hermida‐Prado, Rene Rodriguez, , Mónica Álvarez‐Fernández

This study establishes patient-derived organoids from HNSCC tumors that recapitulate histological, molecular, and therapeutic diversity, enabling personalized therapeutic testing.

bioRxiv · Mar 26, 2026 · PreprintCancer Biology

Loss of Gαq reshapes key fibroblast traits and drives matrix remodeling and aggressive progression of oral cancer tumors

Inmaculada Navarro‐Lérida, Raquel Huertas‐Lárez, Gemma Paredes-Garcia, Dafne García-Mateos, Maria Isabel Jimenez-Lopez, Juan Antonio López, Miguel Á. del Pozo, Saúl Álvarez–Teijeiro, Llara Prieto-Fernández, Juana Maria Garcia-Pedrero, Federico Mayor, Catalina Ribas

This study shows that loss of Gαq in fibroblasts promotes aggressive oral cancer progression by altering ECM remodeling, exosome secretion, and tumor cell migration.

bioRxiv · Mar 12, 2025 · PreprintCancer Biology