Author

Alexandros P. Drainas

BioMed XORCID 0000-0001-9081-9850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Julien SageiD· 2 shared Maya Baron· 2 shared Yoko NishigaiD· 2 shared Aicha R. Mabene· 1 shared Albert Mao LiiD· 1 shared Alec E. DallasiD· 1 shared Ali Taleb AbdallahiD· 1 shared Àlvaro Quintanal-VillalongaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Julien SageORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 31, 2026

Cell state-specific metabolic networks govern ferroptosis versus apoptosis in small cell lung cancer

Jun W. Kim, Christina M. Bebber, Yuqin Dai…·Julien Sage

The paper identifies metabolic differences between ASCL1-high and low SCLC cells, showing that ASCL1-high cells resist ferroptosis via BH4/BH2 antioxidants and are vulnerable to combined cysteine depletion and BH4/BH2 inhibition.

DOI 10.64898/2026.03.27.714827

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintDec 21, 2025

T CELLS promote the growth of small-cell lung carcinoma via an IL-6/CD74 axis

Maya Baron, Zoé Ginestet, Debadrita Bhattacharya…·Julien Sage

The paper shows T cells promote SCLC growth through an IL-6/CD74 axis, and IL-6 blockade enhances immunotherapy effectiveness in SCLC.

1 citation

mouseexperimental assay

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Cancer BiologyCell Death and DifferentiationPeer-reviewedApr 22, 2025

Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

Anthony M. Boutelle, Aicha R. Mabene, David Yao…·Laura Donatella Attardi

The paper identifies ZMAT3 and CDKN1A as key hubs in the p53 tumor suppression network through integrative multiomic analyses in a mouse model.

10 citationstop 5%

mousebulk RNA-seq

𝕏 PostBluesky