Author

Göktuğ Karabiyik

Koç UniversityORCID 0000-0002-0396-7626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A S RitamäkiiD· 1 shared Adam P. CribbsiD· 1 shared Ali Cenk AksuiD· 1 shared Aliisa M. TiihoneniD· 1 shared Arja Jukkola‐VuorineniD· 1 shared Ezgi Ozyerli‐GoknariD· 1 shared Feridun AksuiD· 1 shared Fidan Seker-PolatiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A S RitamäkiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting CBP/p300 Overcomes Acquired Vincristine Resistance in Medulloblastoma

Göktuğ Karabiyik, Ozlem Yedier-Bayram, Feridun Aksu, Tolga Lokumcu, Ali Cenk Aksu, Fidan Seker-Polat, Ezgi Ozyerli‐Goknar, Adam P. Cribbs, Udo C. T. Oppermann, Tugba Bagci Onder

This study identifies CBP/p300 inhibition as a strategy to overcome vincristine resistance in medulloblastoma by targeting genes involved in drug resistance.

bioRxiv · Jul 28, 2026 · PreprintCancer Biology

Hypoxia and Associated Acidosis Generate Cell-Type Specific Myeloid Responses in Glioblastoma

Aliisa M. Tiihonen, Iida Salonen, Iina Koivisto, A S Ritamäki, Serafiina Jaatinen, Tanja Hyvärinen, Johanna Tilvis, Joose Kreutzer, Göktuğ Karabiyik, S Mäntylä, Maryam Mohammadlou, Miina Hoikka, Masi Valkonen, Jürgen Beck, Roland Roelz, , Kirsi J. Rautajoki

The paper investigates how hypoxia and acidosis influence myeloid cell responses in glioblastoma, revealing distinct metabolic adaptations in macrophages versus microglia.

bioRxiv · Feb 28, 2026 · PreprintCancer Biology