Author

Ankit Jain

ETH ZurichORCID 0000-0001-9123-5945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Andrew J. deMelloiD· 2 shared Stavros StavrakisiD· 2 shared Andreas Jakob· 1 shared Christoffel P. S. BadenhorstiD· 1 shared David BednářiD· 1 shared David Damborsky· 1 shared David R. KovariD· 1 shared Flora W. Y. Chiu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Andrew J. deMelloORCID

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2 papers

Recent·Most cited

BiochemistryACS CatalysisPeer-reviewedOct 2, 2026

Uncovering Functional Distant Mutations by Ultra-High-Throughput Screening of Dehalogenases

Hana Faldynová, David R. Kovar, Ankit Jain…·Zbyněk Prokop

This study uses ultrahigh-throughput screening to identify mutations in dehalogenases that modulate substrate access and binding, revealing distal functional effects on enzyme dynamics.

DOI 10.1021/acscatal.6c03694

proteomicsexperimental assay

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ImmunologybioRxivPreprintJun 29, 2026

Droplet single-cell CRISPR screens identify regulators of T cell-mediated target-cell killing

Giulia Saronio, Gaia Antonini, Ankit Jain…·Roger Geiger

The paper uses droplet single-cell CRISPR screening to identify regulators of T cell-mediated target-cell killing and finds that mTORC1 modulation enhances cytotoxic activity.

DOI 10.64898/2026.06.23.734054

humanCRISPR screen

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