Molecular BiologybioRxivPreprint
Xist spatially amplifies SHARP recruitment to balance chromosome-wide silencing and specificity to the X chromosome
Joanna W. Jachowicz, Mackenzie M. Strehle, Abhik K. Banerjee…·Mitchell Guttman
This study shows Xist uses spatial amplification of SHARP to achieve chromosome-wide silencing while maintaining specificity to the X chromosome.
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