RNA promotes the formation of spatial compartments in the nucleus
Sofia A. Quinodoz, Joanna W. Jachowicz, Prashant Bhat, Noah Ollikainen, Abhik K. Banerjee, Isabel Nadine Goronzy, Mario R. Blanco, Peter Chovanec, Amy Y. Chow, Yolanda Markaki, Jasmine Thai, Kathrin Plath, Mitchell Guttman
The paper develops RD-SPRITE to map RNA-DNA and RNA-RNA interactions in 3D nuclear structures, revealing RNA's role in forming compartments that regulate nuclear functions.
Cell · Nov 1, 2021Peer-reviewedGenomics