PhysiologyAmerican Journal of Physiology-Heart and Circulatory PhysiologyPeer-reviewed
Cellular Senescence Mediates Doxorubicin Chemotherapy-Induced Vascular Endothelial Dysfunction: Translational Evidence of Prevention with Senolytic Treatment
Ravinandan Venkatasubramanian, Sophia A. Mahoney, David A. Hutton…·Zachary Stephen Clayton
This study shows that cellular senescence contributes to Doxorubicin-induced vascular endothelial dysfunction and that senolytic treatment can prevent this dysfunction.
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