Sebastian Greiss

Photocaged FLP Recombinase for Precise Spatio-temporal Control of Gene Expression

This paper develops a photocaged FLP recombinase for precise spatio-temporal control of gene expression in C. elegans, demonstrating high efficiency and compatibility with standard imaging wavelengths.

Expanding the Genetic Code of an Animal with Two Non-Canonical Amino Acids

This paper expands the genetic code of C. elegans to incorporate two non-canonical amino acids using orthogonal tRNA-synthetase pairs and photocaged amino acids, enabling optical control of gene expression.

Using a Quadruplet Codon to Expand the Genetic Code of an Animal

This paper introduces a system to use quadruplet codons for incorporating non-canonical amino acids in C. elegans, enabling optical control of gene expression and light-inducible cell ablation.

Precise optical control of gene expression in C. elegans using genetic code expansion and Cre recombinase

This study uses genetic code expansion and optical targeting in C. elegans to selectively activate gene expression in specific neurons and analyze their role in behavior.

Generation of photocaged nanobodies for in vivo applications using genetic code expansion and computationally guided protein engineering

This paper develops photocaged nanobodies for in vivo applications using genetic code expansion and computational methods to control protein interactions with light.