Author

Wei Li

Tsinghua UniversityORCID 0000-0001-9133-461XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Wei Li48 papers · University of California, Irvine

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Guangshuo OuiD· 3 shared Shimin WangiD· 2 shared Yongping ChaiiD· 2 shared Zhengyang GuoiD· 2 shared Chao XieiD· 1 shared Guanghan CheniD· 1 shared Jingyi KeiD· 1 shared Kaiming XuiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioinformatics

Guangshuo OuORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 1, 2026

Hierarchical latent representations reveal protein organization for functional discovery and design

Zhengyang Guo, Zi Wang, Shimin Wang…·Guangshuo Ou

This paper develops a hierarchical sequence-based framework to infer distributed protein organization, identifies novel ciliary proteins, and enables synthetic protein design.

DOI 10.64898/2026.02.14.705947

mouseprotein sequence

𝕏 PostBluesky

GenomicsG3 Genes Genomes GeneticsPeer-reviewedJun 10, 2024

Transposase-Assisted Tagmentation: An Economical and Scalable Strategy for Single-Worm Whole-Genome Sequencing

Zi Wang, Jingyi Ke, Zhengyang Guo…·Guangshuo Ou

The paper introduces a cost-effective WGS method for model organisms to validate missense variant predictions.

5 citations

C. elegansE. coli

𝕏 PostBluesky

Developmental BiologyJournal of Cell SciencePeer-reviewedJul 3, 2020

Spectrin-based Membrane Mechanics Is Asymmetric and Remodels during Neural Development

Ru Jia, Yongping Chai, Chao Xie…·Guangshuo Ou

This study investigates the role of spectrin-based membrane mechanics in neuronal migration and dendrite formation in C. elegans, showing that spectrin's asymmetry and remodeling are critical for proper development.

11 citations

C. elegansexperimental assay

𝕏 PostBluesky