Author

Sharad Kumar Gupta

Indian Institute of Technology GandhinagarORCID 0000-0001-9136-3875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:Arabidopsis· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Dhiraj Devidas BhatiaiD· 3 shared Krupa KansaraiD· 2 shared Vivek ShekhariD· 2 shared Abhijit BiswasiD· 1 shared Ashutosh KumariD· 1 shared Ashutosh KumariD· 1 shared Bhagyesh ParmariD· 1 shared Hema Naveena AiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioengineering

Dhiraj Devidas BhatiaORCID

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3 papers

Recent·Most cited

Programmable DNA nanocages to modulate pollen tube growth via active uptake

Subhojit Ghosh, Vivek Shekhar, Sharad Kumar Gupta, Dhiraj Devidas Bhatia, Subramanian Sankaranarayanan

This paper demonstrates DNA nanocages (TDNs) for targeted delivery of biomolecules into Arabidopsis pollen tubes, modulating growth through actin reorganization and ROS modulation.

bioRxiv · Mar 7, 2026 · PreprintBioengineering

Growth-factor ligand functionalization enhances cellular and in vivo uptake of DNA nanodevices

Abhijit Biswas, N Hema, Krupa Kansara, Bhagyesh Parmar, Vivek Shekhar, Ashutosh Kumar, Sharad Kumar Gupta, Dhiraj Devidas Bhatia

This study shows that functionalizing DNA nanodevices with growth-factor ligands improves their cellular and in vivo uptake and effectiveness.

bioRxiv · Aug 1, 2025 · PreprintBioengineering

Peptide modified, programmable DNA tetrahedra to modulate autophagy in biological systems

Hema Naveena A, Krupa Kansara, Nihal Singh, Sharad Kumar Gupta, Ashutosh Kumar, Dhiraj Devidas Bhatia

This paper introduces a DNA tetrahedron-BH3 peptide nanosystem that selectively induces autophagy by disrupting Beclin 1-Bcl2 interaction, showing reduced ROS and no apoptosis in HeLa cells and zebrafish larvae.

bioRxiv · Nov 3, 2024 · PreprintBioengineering