Synthetic BiologybioRxivPreprint
An Ehrlich-inspired retrobiosynthesis of pharmaceutical scaffolds
Anastasia E.C. Rumpl, Devin Kowalski, Joshua R. Goodhew…·Michael E. Pyne
The paper repurposes the yeast Ehrlich pathway to synthesize pharmaceutical alkaloids using retrobiosynthetic analysis and enzyme screening.
DOI 10.1101/2025.11.10.687684