Author

Carlos A. Rosa

Universidade Federal de Minas GeraisORCID 0000-0002-0056-9075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Katharina O. BarrosiD· 2 shared Alessandro M. VaraniiD· 1 shared Ana Raquel O. SantosiD· 1 shared Anastasia E.C. RumpliD· 1 shared Carlos A. VillarroeliD· 1 shared Carlos Renato MachadoiD· 1 shared Chris Todd HittingeriD· 1 shared Dafne de Oliveira VianeiiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioinformatics

Katharina O. BarrosORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An Ehrlich-inspired retrobiosynthesis of pharmaceutical scaffolds

Anastasia E.C. Rumpl, Devin Kowalski, Joshua R. Goodhew, Mika Hirano, Liam Bogucki, Carlos A. Rosa, Marc‐André Lachance, Michael E. Pyne

The paper repurposes the yeast Ehrlich pathway to synthesize pharmaceutical alkaloids using retrobiosynthetic analysis and enzyme screening.

bioRxiv · Nov 10, 2025 · PreprintSynthetic Biology

The peptide LyeTx I mnΔK induces transcriptomic reprogramming in a novel Multidrug-resistant Acinetobacter baumannii

Frederico Gabriel de Carvalho Oliveira, Katharina O. Barros, Dafne de Oliveira Vianei, Julia Raspante Martins, Jessica Caroline Duarte, Daniela de Laet Souza, Izabela Mamede, Rennan Garcias Moreira, Renato Santana Aguiar, Filipe Alex da Silva, Vera Lúcia dos Santos, Alessandro M. Varani, Thiago Mafra Batista, Carlos Renato Machado, Carlos A. Rosa, , Glória Regina Franco

This study characterizes a new multidrug-resistant Acinetobacter baumannii isolate and evaluates the transcriptomic effects of a synthetic antimicrobial peptide in combination with meropenem.

bioRxiv · Sep 29, 2025 · PreprintBioinformatics

An evolved strain of Spathaspora passalidarum produces ethanol from sugarcane bagasse and switchgrass lignocellulosic hydrolysates

Katharina O. Barros, Kaitlin J. Fisher, Johnathan G. Crandall, Giulia Magni, José Serate, Dan Xie, Yaoping Zhang, Sílvio Silvério da Silva, Trey K. Sato, Chris Todd Hittinger, Carlos A. Rosa

This study evolved Spathaspora passalidarum to produce ethanol from lignocellulosic hydrolysates by improving tolerance to inhibitors like acetic acid.

bioRxiv · Sep 26, 2025 · PreprintGenomics

An integrative taxonomy approach reveals Saccharomyces chiloensis sp. nov. as a newly discovered species from Coastal Patagonia

Tomás A. Peña, Pablo David Villarreal, Nicolas Agier, Matteo De Chiara, Tomas Barría, Kamila Urbina, Carlos A. Villarroel, Ana Raquel O. Santos, Carlos A. Rosa, Roberto F. Nespolo, Gianni Liti, Gilles Fischer, Francisco A. Cubillos

The paper identifies a new Saccharomyces species, S. chiloensis sp. nov., using integrative taxonomy methods, showing genetic and reproductive divergence from S. uvarum.

PLoS Genetics · Sep 6, 2024Peer-reviewedGenetics