Author

Brian P. Keegan

Baylor College of MedicineORCID 0000-0001-9140-8690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 1 Assay:protein structure· 1 Organism:yeast· 1

Frequent Co-Authors

Bin ZhaniD· 2 shared Cristina PovedaiD· 2 shared Jason T. KimataiD· 2 shared Jeroen B. K. PolletiD· 2 shared Junfei WeiiD· 2 shared Jungsoon LeeiD· 2 shared Leroy VersteegiD· 2 shared María Elena BottazziiD· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Bin ZhanORCID

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2 papers

Recent·Most cited

Molecular BiologyVaccinePeer-reviewedMay 8, 2022

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Jeroen B. K. Pollet, Ulrich Strych, Wen‐Hsiang Chen…·María Elena Bottazzi

This study evaluates a SARS-CoV-2 RBD subunit vaccine in mice, showing that adding CpG enhances immune response and neutralizing antibodies against multiple variants.

42 citationstop 3%

mouseexperimental assay

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Molecular BiologyProtein Expression and PurificationPeer-reviewedOct 21, 2021

Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate

Wen‐Hsiang Chen, Jeroen B. K. Pollet, Ulrich Strych…·María Elena Bottazzi

This paper describes the development of a recombinant SARS-CoV-2 RBD vaccine candidate produced in yeast, showing high purity, stability, and immunogenicity in mice.

49 citations

yeastprotein structure

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