Author

Bin Zhan

Baylor College of MedicineORCID 0000-0002-6884-9452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Brian P. KeeganiD· 2 shared Cristina PovedaiD· 2 shared Jason T. KimataiD· 2 shared Jeroen B. K. PolletiD· 2 shared Junfei WeiiD· 2 shared Jungsoon LeeiD· 2 shared Leroy VersteegiD· 2 shared María Elena BottazziiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Brian P. KeeganORCID

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Author profile →

3 papers

Recent·Most cited

Evaluation of a novel Tc-24 recombinant antigen ELISA for serologic testing for Trypanosoma cruzi in dogs

Rojelio Mejía, Guilherme G. Verocai, Ilana A. Mosley, Ashley B. Saunders, Bin Zhan, Lindsey R. Vongthavaravat, Rachel E. Busselman, Sarah A. Hamer

This study evaluates a new Tc-24 recombinant antigen ELISA for detecting anti-T. cruzi antibodies in dogs, showing high sensitivity and specificity compared to existing tests.

Veterinary Medicine and Science · Aug 19, 2025Peer-reviewedZoology

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Jeroen B. K. Pollet, Ulrich Strych, Wen‐Hsiang Chen, Leroy Versteeg, Brian P. Keegan, Bin Zhan, Junfei Wei, Zhuyun Liu, Jungsoon Lee, Rahki Kundu, Rakesh Adhikari, Cristina Poveda, María José Villar, Syamala Rani Thimmiraju, Brianna Lopez, , María Elena Bottazzi

This study evaluates a SARS-CoV-2 RBD subunit vaccine in mice, showing that adding CpG enhances immune response and neutralizing antibodies against multiple variants.

Vaccine · May 8, 2022Peer-reviewedMolecular Biology

Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate

Wen‐Hsiang Chen, Jeroen B. K. Pollet, Ulrich Strych, Jungsoon Lee, Zhuyun Liu, Rakhi Tyagi Kundu, Leroy Versteeg, María José Villar, Rakesh Adhikari, Junfei Wei, Cristina Poveda, Brian P. Keegan, Aaron Oakley Bailey, Yilin Chen, Portia M. Gillespie, , María Elena Bottazzi

This paper describes the development of a recombinant SARS-CoV-2 RBD vaccine candidate produced in yeast, showing high purity, stability, and immunogenicity in mice.

Protein Expression and Purification · Oct 21, 2021Peer-reviewedMolecular Biology