Author

Jason T. Kimata

Baylor College of MedicineORCID 0000-0002-0504-0090Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Bin ZhaniD· 2 shared Brian P. KeeganiD· 2 shared Cristina PovedaiD· 2 shared Jeroen B. K. PolletiD· 2 shared Junfei WeiiD· 2 shared Jungsoon LeeiD· 2 shared Leroy VersteegiD· 2 shared María Elena BottazziiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Bin ZhanORCID

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Author profile →

4 papers

Recent·Most cited

Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and 1 Mycobacterium tuberculosis in macrophages and humanized mice

Vipul Kumar Singh, Abhishek Mishra, Khanghy Truong, José Alejandro Bohórquez, Suman Sharma, Arshad Khan, Franz Bracher, Kangling L Zhang, Janice Jones Endsley, Mark A. Endsley, Andrew P. Rice, Jason T. Kimata, Guohua Yi, Chinnaswamy Jagannath

This study shows that Sirt2 inhibition reduces HIV-1 and Mtb replication in macrophages and humanized mice, suggesting a dual therapeutic strategy.

Molecular Therapy · Mar 25, 2026Peer-reviewedImmunology

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Jeroen B. K. Pollet, Ulrich Strych, Wen‐Hsiang Chen, Leroy Versteeg, Brian P. Keegan, Bin Zhan, Junfei Wei, Zhuyun Liu, Jungsoon Lee, Rahki Kundu, Rakesh Adhikari, Cristina Poveda, María José Villar, Syamala Rani Thimmiraju, Brianna Lopez, , María Elena Bottazzi

This study evaluates a SARS-CoV-2 RBD subunit vaccine in mice, showing that adding CpG enhances immune response and neutralizing antibodies against multiple variants.

Vaccine · May 8, 2022Peer-reviewedMolecular Biology

Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate

Wen‐Hsiang Chen, Jeroen B. K. Pollet, Ulrich Strych, Jungsoon Lee, Zhuyun Liu, Rakhi Tyagi Kundu, Leroy Versteeg, María José Villar, Rakesh Adhikari, Junfei Wei, Cristina Poveda, Brian P. Keegan, Aaron Oakley Bailey, Yilin Chen, Portia M. Gillespie, , María Elena Bottazzi

This paper describes the development of a recombinant SARS-CoV-2 RBD vaccine candidate produced in yeast, showing high purity, stability, and immunogenicity in mice.

Protein Expression and Purification · Oct 21, 2021Peer-reviewedMolecular Biology

Full-coverage native RNA sequencing of HIV-1 viruses

Alejandro Rafael Gener, Jason T. Kimata

This study uses native RNA sequencing to fully characterize HIV-1 genomes, achieving full-length coverage in some isolates and identifying strain-specific transcriptional signals.

bioRxiv · Nov 19, 2019 · PreprintGenomics