PathologyJCI InsightPeer-reviewed
PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis
Thomas H. Sisson, John J. Osterholzer, Lisa Leung…·Daniel A. Lawrence
The paper identifies SorlA as a novel PAI-1 interactor required for lung fibrosis, showing SorlA deficiency protects against fibrosis in mice and SorlA is upregulated in human IPF lung tissue.
7 citations