Author

Olli Lohi

Tampere University HospitalORCID 0000-0001-9195-0797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Merja HeinäniemiiD· 2 shared Ville HautamäkiiD· 2 shared Anna VähärautioiD· 1 shared Christian SommeraueriD· 1 shared Dhifaf SarhaniD· 1 shared Felix HaglundiD· 1 shared Frederik KirkiD· 1 shared Hildur HelgadóttiriD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Merja HeinäniemiORCID

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3 papers

Recent·Most cited

CyStainer: A transformer-based variational autoencoder for robust marker imputation in high-parameter cytometry

Konstantin Ivanov, Mouhamad Al Moussawy, Frederik Kirk, Samuli Rounioja, Olli Lohi, Lars Rønn Olsen, Signe Modvig, Ville Hautamäki, Merja Heinäniemi

CyStainer imputes markers in high-parameter cytometry data without shared markers, outperforming existing methods in panel merging and dataset integration.

bioRxiv · Jun 30, 2026 · PreprintBioinformatics

Principles of subclonal gene dosage across human cancer

Sólrún Kolbeinsdóttir, Vasilios Zachariadis, Muyi Yang, Luuk A. Broeils, Christian Sommerauer, Huaitao Cheng, Xinsong Chen, Yingbo Lin, Matías Marín Falco, Johanna Hynninen, Sampsa Hautaniemi, Yizhe Sun, Olli Lohi, Merja Heinäniemi, Suzanne Egyhazi Brage, , Martin Enge

The paper analyzes subclonal gene dosage effects in cancer using DNTR-seq, finding additive and compensatory transcriptional impacts and identifying transient clonality in ovarian and soft tissue sarcomas.

bioRxiv · Mar 18, 2026 · PreprintCancer Biology

Data-driven characterization of molecular phenotypes across heterogenous sample collections

Juha Mehtonen, Petri Pölönen, Sergei Häyrynen, Jake Lin, Thomas Liuksiala, K Granberg, Olli Lohi, Ville Hautamäki, Matti Nykter, M. Heinäniemi

The paper develops a method for stratifying molecular profiles across datasets and applies it to hematological malignancies, revealing differential DNA methylation in a leukemia cluster.

bioRxiv · Jan 15, 2018 · PreprintBioinformatics