Author

Petri Pölönen

St. Jude Children's Research HospitalORCID 0000-0001-6128-9985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Charles Grenfell MullighaniD· 2 shared Aarthi RavindraniD· 1 shared Ahnaf Tausif· 1 shared André AlmeidaiD· 1 shared Anna K. GolebiewskiiD· 1 shared Anu ToropaineniD· 1 shared Béatrice LintermansiD· 1 shared Belinda M. GiardineiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

Charles Grenfell MullighanORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 29, 2026

SOX11 stimulates γδ T-cell differentiation and synergizes with LMO2 and MYCN to drive γδ-like T-cell acute lymphoblastic leukemia

André Almeida, Igor Fijałkowski, Kasper Thorhauge Christensen…·Steven Goossens

This study identifies SOX11 as a driver of γδ-like T-cell acute lymphoblastic leukemia, showing its cooperation with LMO2 and MYCN to promote leukemogenesis.

DOI 10.64898/2026.07.28.741231

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJun 30, 2026

LDB1-dependent enhancer connectivity defines T-cell leukemia identities and masks metabolic vulnerabilities

Rahul S. Bhansali, Juan Sebastian Long, Petri Pölönen…·Gerd A. Blobel

The paper identifies LDB1-dependent enhancer connectivity as critical for T-cell leukemia subtypes and reveals a metabolic vulnerability exploitable by statins.

DOI 10.64898/2026.06.29.733236

humanbulk RNA-seq

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GeneticsArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedApr 11, 2024

Coronary Artery Disease risk variant dampens the expression of CALCRL by reducing HSF binding to shear stress responsive enhancer in endothelial cells

Ilakya Selvarajan, Miika Kiema, Ru‐Ting Huang…·Minna Unelma Kaikkonen

The paper identifies a CAD risk SNP rs880890 in an endothelial enhancer that reduces CALCRL expression by impairing HSF binding under shear stress.

6 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintJan 15, 2018

Data-driven characterization of molecular phenotypes across heterogenous sample collections

Juha Mehtonen, Petri Pölönen, Sergei Häyrynen…·M. Heinäniemi

The paper develops a method for stratifying molecular profiles across datasets and applies it to hematological malignancies, revealing differential DNA methylation in a leukemia cluster.

1 citation

humanbulk RNA-seq

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