Author

Olga A. Rogachevskaja

Russian Academy of SciencesORCID 0000-0001-9204-2387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:imaging· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ekaterina A. DymovaiD· 2 shared Polina D. KotovaiD· 2 shared Stanislav S. Kolesnikov· 2 shared Evgeniya A. VoronovaiD· 1 shared Oleg O. LyaminiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ekaterina A. DymovaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 6, 2025

Serotonin 5-HT2C receptor as a cellular target of PI3K inhibitor LY294002 and its analog LY303511

Polina D. Kotova, Ekaterina A. Dymova, Oleg O. Lyamin…·Stanislav S. Kolesnikov

This study shows that LY294002 and LY303511 affect serotonin-induced Ca2+ signaling via distinct mechanisms involving the 5-HT2C receptor, suggesting off-target effects beyond their intended PI3K inhibition.

DOI 10.1101/2025.11.06.687025

mouseimaging

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Pharmacology & ToxicologybioRxivPreprintMay 5, 2024

PI3 kinase-unrelated effects of LY294002 and LY303511 on serotonin-induced Ca2+ and cAMP signaling

Polina D. Kotova, Ekaterina A. Dymova, Olga A. Rogachevskaja, Stanislav S. Kolesnikov

This study investigates the effects of PI3K inhibitors LY294002 and LY303511 on serotonin-induced Ca2+ and cAMP signaling, revealing PI3K-unrelated receptor-specific effects.

DOI 10.1101/2024.05.05.592569

humanimaging

𝕏 PostBluesky