Polina D. Kotova

This study shows that LY294002 and LY303511 affect serotonin-induced Ca2+ signaling via distinct mechanisms involving the 5-HT2C receptor, suggesting off-target effects beyond their intended PI3K inhibition.

This study shows that the PI3K inhibitor PI828 blocks Ca2+ responses to aminergic agonists through an unknown mechanism unrelated to PI3K inhibition, while wortmannin has minimal effect.

This study investigates the effects of PI3K inhibitors LY294002 and LY303511 on serotonin-induced Ca2+ and cAMP signaling, revealing PI3K-unrelated receptor-specific effects.