Author

Chengcheng Jin

University of PennsylvaniaORCID 0000-0001-9207-3191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Abigail Wong-RolleiD· 1 shared Chen Ning ZhaoiD· 1 shared Edward C. SchromiD· 1 shared Jyh Liang HoriD· 1 shared Luke F. VistainiD· 1 shared Qiang Dong· 1 shared Ronald N. GermainiD· 1 shared Wanjing ShangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Abigail Wong-RolleORCID

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1 paper

Recent·Most cited

PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells

Jyh Liang Hor, Edward C. Schrom, Abigail Wong-Rolle, Luke F. Vistain, Wanjing Shang, Qiang Dong, Chen Ning Zhao, Chengcheng Jin, Ronald N. Germain

This study identifies PD-1's role in maintaining stem-like CD8+ T cells through TCR affinity regulation and signaling fine-tuning, showing its impact on immunotherapy efficacy.

Nature · Nov 26, 2025Peer-reviewedImmunology