Author

Chen Ning Zhao

National Cancer InstituteORCID 0000-0002-1494-5983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Abigail Wong-RolleiD· 2 shared Edward C. SchromiD· 2 shared Arya J. Bahrami· 1 shared Bo ZhangiD· 1 shared Chengcheng JiniD· 1 shared Christopher Simon HouriganiD· 1 shared Eddie Martin· 1 shared Gege GuiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Abigail Wong-RolleORCID

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3 papers

Recent·Most cited

ImmunologyNaturePeer-reviewedNov 26, 2025

PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells

Jyh Liang Hor, Edward C. Schrom, Abigail Wong-Rolle…·Ronald N. Germain

This study identifies PD-1's role in maintaining stem-like CD8+ T cells through TCR affinity regulation and signaling fine-tuning, showing its impact on immunotherapy efficacy.

56 citationstop 1%

humanimaging

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Cancer BiologyScience AdvancesPeer-reviewedJul 9, 2025

✦ In-depth digest

Single Cell Spatial Transcriptomics Reveals Immunotherapy-Driven Bone Marrow Niche Remodeling in AML

Gege Gui, Molly A. Bingham, Julius R. Herzog…·Chen Ning Zhao

CosMx spatial transcriptomics of bone marrow from 6 refractory/relapsed AML patients shows CD14+ monocytes rising in leukemia-cell neighborhoods after pembrolizumab in responders, dendritic cells in nonresponders.

26 citationstop 1%

humanspatial transcriptomics

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Developmental BiologyNature CommunicationsPeer-reviewedOct 14, 2023

KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors

Bo Zhang, Chen Ning Zhao, Wenchen Shen…·Yan Zhou

This paper shows that KDM2B suppresses Wnt signaling in neural progenitors to regulate hippocampal development and morphology.

14 citations

mousestatistical model

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