Author

Matthew J. Gavin

University of PennsylvaniaORCID 0000-0001-9245-172XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

David MerrickiD· 1 shared Dominic SantoleriiD· 1 shared Patrick SealeiD· 1 shared Paul M. TitchenelliD· 1 shared Ryan P. CalhouniD· 1 shared Sarah TraynoriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperPhysiology

David MerrickORCID

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1 paper

Recent·Most cited

PhysiologyMolecular MetabolismPeer-reviewedJun 18, 2026

Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant

Dominic Santoleri, Sarah Traynor, Ryan P. Calhoun…·Paul M. Titchenell

This study investigates how the GKRP P446L variant affects hepatic lipid and cholesterol metabolism by reducing GCK activity and increasing cholesterol synthesis.

DOI 10.1016/j.molmet.2026.102404

mouseproteomics

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