Author

Sarah Traynor

University of PennsylvaniaORCID 0000-0001-5484-2180Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

David MerrickiD· 2 shared Patrick SealeiD· 2 shared Ryan P. CalhouniD· 2 shared Camille E. M Piquet· 1 shared Dominic SantoleriiD· 1 shared Josephine M. E. TaniD· 1 shared Karima Drareni· 1 shared Lan ChengiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

David MerrickORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 28, 2026

SOX4 Reprograms Adipose Stromal Cells into a Cancer-Associated Fibroblast-like State to Drive Metabolic Disease

Karima Drareni, Ryan P. Calhoun, Lan Cheng…·Patrick Seale

This study shows that SOX4 reprograms adipose stromal cells into CAF-like cells in obesity, promoting metabolic disease through TGFβ and MDK signaling.

DOI 10.64898/2026.09.24.754142

mousehuman

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PhysiologyMolecular MetabolismPeer-reviewedJun 18, 2026

Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant

Dominic Santoleri, Sarah Traynor, Ryan P. Calhoun…·Paul M. Titchenell

This study investigates how the GKRP P446L variant affects hepatic lipid and cholesterol metabolism by reducing GCK activity and increasing cholesterol synthesis.

DOI 10.1016/j.molmet.2026.102404

mouseproteomics

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