Alberto M. Pendás

This study shows Set is essential for chromosome alignment and Cohesin cleavage in oocyte meiosis, functioning through Aurora B regulation and chromatin environment modulation, independent of PP2A-B56 interaction.

This study shows that full-length BEND2 is not needed for male fertility but is essential for establishing the ovarian reserve in mice.

The paper quantifies transcriptional dynamics in mouse spermatogonia during meiosis, identifying a transcriptional slowdown and mRNA stabilization event that coordinates meiotic gene expression.

This paper identifies a cryptic BRCA2 repeated motif that binds to HSF2BP oligomers but does not affect meiotic recombination.

The paper identifies a missense variant in HSF2BP linked to POI, showing it impairs meiotic recombination by affecting its interaction with MIDAP and reducing recombinase activity.

This study shows that PSMA8 deficiency in mice leads to meiotic exit defects and infertility despite normal meiotic DNA repair and recombination.