Telomere 3'-overhang attrition and persistent telomeric DNA damage response in failing human hearts
Bo Ye, Liang Shang, Xun Yuan…·Faqian Li
The paper investigates telomere dysfunction in failing human hearts, finding 3'-overhang attrition and DNA damage responses in cardiomyocytes from idiopathic dilated cardiomyopathy and ischemic heart disease.