Jinbao Liu

This study identifies a transcriptional circuit in CML blast crisis that drives disease progression and shows mebendazole can inhibit it, offering a potential therapeutic strategy.

This study shows that homeostatic activation of 26S proteasomes by PKA protects against brain and cardiac dysfunction in Alzheimer's disease mice.

This study shows that Ser14-phosphorylated Rpn6 protects against tauopathy-related brain and heart pathology by maintaining proteostasis.

This study identifies RBX2 as a key component of the CRL5 ubiquitin ligase that regulates mitophagy in cardiomyocytes independently of PARKIN, maintaining cardiac homeostasis.

This study uses single-nucleus multiomics to uncover drought-driven gene regulatory mechanisms in Arabidopsis, identifying cell type-specific markers and regulatory networks.

This study identifies widespread N6-methyladenine (6mA) modification in the human genome, links it to gene expression, and shows its role in cancer by demonstrating reduced 6mA levels in tumors.