Caitlin E Leedy

This study investigates the role of striatal cholinergic interneuron pathology and muscarinic signaling in dystonia using a mouse model, showing that ChI degeneration contributes to motor dysfunction but is not required for antimuscarinic drug effects.

The paper shows that secondary visual areas in mice are necessary for a simple visual task, even when primary visual cortex is intact.

The paper tests inhibition-stabilized network (ISN) models in mouse cortex and finds evidence for ISN operation across multiple areas and states.