Hannah C Goldbach

Cholinergic-dependent dopamine signals in mouse dorsomedial striatum are regulated by frontal but not sensory cortices

The paper shows that visual stimuli evoke dopamine in the dorsomedial striatum via cholinergic-dependent mechanisms, driven by frontal cortices rather than sensory cortices.

A synaptic mechanism for encoding the learned value of action-derived safety

The paper identifies a thalamostriatal circuit mechanism by which internally constructed outcomes, like safety, acquire motivational value through synaptic plasticity in mice.

Brain insulin signaling restores deficits in striatal dopamine release in overweight male mice with preexisting low D2-receptor expression

This study shows that low striatal D2 receptor density in male mice predisposes to obesity-like traits through early dopaminergic dysfunction, which is later compensated by brain insulin hypersensitivity.

Excitation creates a distributed pattern of cortical suppression due to varied recurrent input

The paper shows optogenetic input to mouse V1 excitatory neurons creates salt-and-pepper patterns of excitation and suppression, with responses not strongly predicted by direct input.

Performance in even a simple perceptual task depends on mouse secondary visual areas

The paper shows that secondary visual areas in mice are necessary for a simple visual task, even when primary visual cortex is intact.

Inhibition stabilization is a widespread property of cortical networks

The paper tests inhibition-stabilized network (ISN) models in mouse cortex and finds evidence for ISN operation across multiple areas and states.