Author

Bradley Akitake

National Institutes of HealthORCID 0000-0002-1817-4573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:benchmarking· 2 Assay:electronic health records· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Mark H. HistediD· 4 shared Anna J. LiiD· 2 shared Caitlin E LeedyiD· 2 shared Hannah C GoldbachiD· 2 shared Paul K. LaFosseiD· 2 shared Yanting DengiD· 2 shared Zhishang ZhouiD· 2 shared Alessandro SanzeniiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Mark H. HistedORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Amplified cortical neural responses as animals learn to use novel activity patterns

Bradley Akitake, Hannah M. Douglas, Paul K. LaFosse, Manuel Beirán, Ciana E. Deveau, Jonathan F. O’Rawe, Anna J. Li, Lauren Ryan, Samuel P. Duffy, Zhishang Zhou, Yanting Deng, Kanaka Rajan, Mark H. Histed

The paper shows that mice learning to use novel optogenetic activity patterns in V1 experience amplified neural responses, suggesting cortical plasticity improves behavioral performance.

Current Biology · May 5, 2023Peer-reviewedNeuroscience

Bicistronic expression of a high-performance calcium indicator and opsin yields stable, robust cortical expression for holographic two-photon stimulation

Paul K. LaFosse, Zhishang Zhou, Nina G. Friedman, Yanting Deng, Anna J. Li, Bradley Akitake, Mark H. Histed

The paper introduces a bicistronic AAV vector that co-expresses GCaMP8s and stChrimsonR in mice, enabling stable and robust two-photon holographic stimulation and imaging of cortical neurons.

eNeuro · Mar 1, 2023Peer-reviewedNeuroscience

Performance in even a simple perceptual task depends on mouse secondary visual areas

Hannah C Goldbach, Bradley Akitake, Caitlin E Leedy, Mark H. Histed

The paper shows that secondary visual areas in mice are necessary for a simple visual task, even when primary visual cortex is intact.

eLife · Feb 1, 2021Peer-reviewedNeuroscience

Inhibition stabilization is a widespread property of cortical networks

Alessandro Sanzeni, Bradley Akitake, Hannah C Goldbach, Caitlin E Leedy, Nicolas Brunel, Mark H. Histed

The paper tests inhibition-stabilized network (ISN) models in mouse cortex and finds evidence for ISN operation across multiple areas and states.

eLife · Jun 29, 2020Peer-reviewedNeuroscience