Cancer BiologybioRxivPreprint
Stability of c-Myc protein differentiates Ras oncogene addiction and MAPK pathway dependency in Ras-mutant multiple myeloma
Ji Luo, Yeon‐Hwa Lee, Christophe Cataisson…·Beverly A. Mock
This study shows that c-Myc protein stability determines the response of Ras-mutant multiple myeloma cells to RAS and MEK inhibitors, suggesting direct RAS targeting is more effective.
DOI 10.64898/2026.08.06.743109