Beverly A. Mock

This study shows that c-Myc protein stability determines the response of Ras-mutant multiple myeloma cells to RAS and MEK inhibitors, suggesting direct RAS targeting is more effective.

This study identifies a compensatory cyclin D2 response as a mechanism conferring trametinib resistance in canine mucosal melanoma.

This study shows that tRNA acetylation regulates stress signaling in mammals by affecting ribosome function and interacting with the Gcn2 kinase.

This study shows that Top3b loss accelerates lymphoma development and causes immune dysregulation in mice through R-loop accumulation and immune signaling activation.