Author

Alicia Damm

Centre National de la Recherche ScientifiqueORCID 0000-0001-9291-8545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Abdou Rachid ThiamiD· 2 shared Bianca M. EschiD· 2 shared Florian FröhlichiD· 2 shared Carolin KörneriD· 1 shared Carolin WillneriD· 1 shared Jennifer L. SapiaiD· 1 shared Lionel Foret· 1 shared Lisa KauffmanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Abdou Rachid ThiamORCID

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2 papers

Recent·Most cited

Lipid Droplet Targeting Drives Substrate Access during Very Long Chain Fatty Acid Activation by Fat1

Carolin Willner, Jennifer L. Sapia, Bianca M. Esch, Pia Erdbrügger, Lisa Kauffmann, Alicia Damm, Sergej Limar, Sebastian Eising, Stefan Walter, Abdou Rachid Thiam, Carolin Körner, Stefano Vanni, Florian Fröhlich

This study shows lipid droplets are the site of VLCFA activation by Fat1, with Fat1 targeting LDs via an amphipathic helix and using a hydrophobic cavity to access substrates.

bioRxiv · Feb 11, 2026 · PreprintBiochemistry

Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement

Alicia Damm, Mohyeddine Omrane, Ozren Stojanović, Bianca M. Esch, Mehdi Zouiouich, Maxime Carpentier, Robin W. Klemm, Florian Fröhlich, Lionel Foret, Abdou Rachid Thiam

The paper identifies steric repulsion as a mechanism regulating ER-to-LD protein movement, showing high-affinity proteins exclude lower-affinity ones during adipocyte differentiation.

Science Advances · Sep 24, 2025Peer-reviewedBiophysics