Maxime Carpentier

Tripartite ER-Mitochondria-Lipid Droplets contact sites control adipocyte metabolic flexibility

This study shows that Seipin regulates tripartite ER-mitochondria-lipid droplet contact sites, which are critical for adipocyte lipid storage and metabolic flexibility.

Extracellular vesicles carrying surface-anchored adiponectin prevent obesity-related metabolic complications by enhancing insulin sensitivity

This study shows that extracellular vesicles with surface-anchored adiponectin improve insulin sensitivity and reduce obesity-related metabolic issues in mice.

Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement

The paper identifies steric repulsion as a mechanism regulating ER-to-LD protein movement, showing high-affinity proteins exclude lower-affinity ones during adipocyte differentiation.

Seipin Regulates Caveolin-1 Trafficking and Organelle Crosstalk

This study shows that seipin regulates CAV1 trafficking and organelle interactions by controlling lipid metabolism and membrane order, impacting cellular homeostasis and metabolic disorders.