David Fernando Plaza

Structure and function of a fungal AB toxin-like chimerolectin involved in anti-nematode defense

The paper characterizes CCTX2, a fungal chimerolectin toxin, revealing its structure and mechanism of nematode toxicity through cryo-EM and functional assays.

Uncovering the genetic diversity of the malaria parasite antigen MSP2 across Sub-Saharan Africa

The paper analyzes genetic diversity of the malaria parasite antigen MSP2 in Sub-Saharan Africa using PCR and long-read sequencing, revealing extensive sequence variation and regional prevalence patterns.

Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate merozoite surface protein 2

This study examines IgG responses to Plasmodium falciparum MSP2, finding that naturally acquired antibodies do not target conserved termini but instead recognize variable regions and linear epitopes.

A genomic platform for epidemiological surveillance and vaccine antigen discovery using long-read amplicon sequencing

The paper introduces a genomic platform using long-read sequencing to monitor pathogen diversity and identify vaccine antigens in multiclonal infections.