Author
Northwestern UniversityORCID 0000-0001-9301-7132Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Amanda Becker, Connor W. Lantz, Aparna Anathakrishman…·Edward Benjamin Thorp
This study shows that myeloid Hif1 is essential for neonatal cardiac regeneration via IGF-1 signaling, as its loss impairs regenerative function and increases myocardial scarring.
Xuebin Fu, Conrad L. Epting, Anshuman Sinha…·Zhi‐Dong Ge
This study shows H19 upregulation in HLHS impairs mitophagy and increases ischemic vulnerability in immature hearts and cardiomyocytes.
Amanda Becker, Mallory E. Filipp, Connor W. Lantz…·Edward Benjamin Thorp
The paper identifies age-specific secretome differences in macrophages under hypoxia and LPS, showing neonatal macrophages have anti-inflammatory, regenerative properties dependent on HIF-1, while adult macrophages show pro-inflammatory, glycolytic responses.