Author

Zhi‐Dong Ge

Northwestern UniversityORCID 0000-0002-7045-0846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anshuman Sinha· 2 shared Connor W. LantziD· 2 shared Edward Benjamin ThorpiD· 2 shared Kristofor E. GlintoniD· 2 shared Xuebin FuiD· 2 shared Agata Bileweska· 1 shared Akash Puvvala· 1 shared Amanda BeckeriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

Anshuman Sinha

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Neonatal Myeloid Hypoxia Response Promotes a Cardiac Regenerative Response through Insulin-Like Growth Factor

Amanda Becker, Connor W. Lantz, Aparna Anathakrishman, Matthew DeBerge, Kristofor E. Glinton, Zhi‐Dong Ge, Edward Benjamin Thorp

This study shows that myeloid Hif1 is essential for neonatal cardiac regeneration via IGF-1 signaling, as its loss impairs regenerative function and increases myocardial scarring.

bioRxiv · Apr 21, 2026 · PreprintImmunology

Machine Learning Identifies Distinct Treg-Mediated Remodeling in HFpEF Hearts Treated with Neonatal Mesenchymal Stem Cells and Their Secretome

Zhi‐Dong Ge, Jonghyeuk Han, Felipe Takaesu, Rachana Mishra, Sudhish Sharma, Ling Chen, Xuebin Fu, Mallory E. Filipp, Ching Man Wai, Ning‐Yi Shao, Anshuman Sinha, Progyaparamita Saha, Akash Puvvala, Luna Ventura, Sonia Thakkar, , Sunjay Kaushal

This study uses machine learning to identify Treg-mediated mechanisms by which nMSCs and their secretome improve diastolic function in HFpEF.

bioRxiv · Jan 30, 2026 · PreprintPhysiology

LncRNA H19 Upregulation Links Hypoplastic Left Heart Syndrome to Impaired PINK1/Parkin-Mediated Mitophagy and Ischemic Vulnerability

Xuebin Fu, Conrad L. Epting, Anshuman Sinha, Michael C. Mongé, Ming Zhao, Kristofor E. Glinton, Swetha Thirukannamangai Krishnan, My Linh Thi Nguyen, V. Joseph Dudley, Gregory B. Waypa, Pedro G. Lara, Tarek Kishawi, Connor W. Lantz, David Scott Winlaw, Paul T. Schumacker, , Zhi‐Dong Ge

This study shows H19 upregulation in HLHS impairs mitophagy and increases ischemic vulnerability in immature hearts and cardiomyocytes.

bioRxiv · Dec 19, 2025 · PreprintGenomics