Molecular BiologybioRxivPreprint
Circular mRNA encoded PROTAC (RiboPROTAC) as a new platform for the degradation of intracellular therapeutic targets
Jiali Yang, Jiaojiao Sun, Jiafeng Zhu…·Chijian Zuo
This paper introduces RiboPROTAC, a new platform using circular mRNA to degrade intracellular proteins, demonstrating its effectiveness in degrading GFP and PCNA with functional and immunological effects.
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