Seppo Juhani Vainio

The paper develops a chimeric model to study kidney vasculature development, showing that CD31+/CD146+ endothelial progenitors are essential for early kidney vasculature formation.

This study isolates and characterizes cloudberry-derived nanovesicles, showing they have antioxidant effects, modulate cell viability, and contain bioactive molecules relevant for skin applications.

This study shows FGF8 promotes chemokinesis in mouse nephron progenitor cells, facilitating their condensation around ureteric buds.

This study investigates branching morphogenesis in the embryonic mammary gland using ex vivo and in vivo techniques, revealing stochastic branching patterns and pathway-dependent regulation.

This paper uses a Cellular Potts Model to simulate cell movement and aggregation during kidney development, showing that chemoattractant secretion and cell adhesion differences drive NP cell patterning.

This study shows that specific collagen XVIII isoforms regulate ureteric branching morphogenesis through their TSP1-like domain in kidney development.

This study develops a method to generate ureteric bud progenitor cells from mouse embryonic stem cells, which can induce nephrogenesis when co-cultured with metanephric mesenchyme.