Artem B. Isaev

Water-mass origin and transformation shapes seawater microbiomes in the northeastern Barents Sea and the St. Anna Trough

The study links seawater microbiome composition to water-mass origin and transformation in the northeastern Barents Sea and St. Anna Trough, identifying distinct microbial signatures for different water masses.

H-NS silences antiviral immunity through 3D chromatin compaction

This study shows H-NS silences bacterial antiviral immunity by compacting chromatin, and its deletion enhances phage defense in E. coli.

OLD sentinel: an abortive tRNase surveys phage replication and DNA defects in RecBCD-compromised cells

This paper characterizes OLD, an abortive immunity protein, revealing its structure and activation mechanism in response to phage replication and DNA defects in RecBCD-compromised cells.

Phages infecting the common gut commensal Escherichia coli HS reveal tropism for its Klebsiella-like capsule

The paper identifies phages infecting E. coli HS, shows their resistance to restriction via modifications, and links phage infection to a Klebsiella-like capsule.

Taxonomically different symbiotic communities of sympatric Arctic sponge species show functional similarity with specialization at species level

The paper analyzes microbiomes of three sympatric Arctic sponge species, finding functional convergence and specialization within their symbiotic communities, with shifts linked to temperature changes.

Specificity and Mechanism of tRNA cleavage by the AriB Toprim nuclease of the PARIS bacterial immune system

The paper identifies additional tRNA targets of the AriB nuclease in the PARIS system and shows that phage-encoded tRNAs can inhibit this defense.

A census of anti-CRISPR proteins reveals AcrIE9 as an inhibitor of Escherichia coli K12 Type IE CRISPR-Cas system

The paper identifies AcrIE9 as an inhibitor of E. coli K12 Type IE CRISPR-Cas system through a census of anti-CRISPR proteins in Enterobacterales.

Molecular basis of foreign DNA recognition by BREX anti-phage immunity system

This study elucidates the molecular mechanism of BREX anti-phage immunity by showing how BrxX methyltransferase recognizes DNA and forms an immune complex to protect against phage infection.

Benchmarking DNA Isolation Methods for Marine Metagenomics Studies

This study benchmarks DNA isolation methods for marine metagenomics by evaluating eight kits across three sample types, focusing on quality, contamination, and community composition.