Author

Sean M. Vargas

The University of Texas at San AntonioORCID 0000-0001-9348-980XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aditi Karmakar· 1 shared Alec Bagwell· 1 shared Alexander D. LemenzeiD· 1 shared Andrew Hayden· 1 shared Brian P. HermanniD· 1 shared Catrina C. FronickiD· 1 shared Charles A. WhittakeriD· 1 shared Ching Man WaiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Aditi Karmakar

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Multi-site Assessment of Methods for Cell Preservation Upstream of Single Cell RNA Sequencing

Fred Kolling, Jessica W. Podnar, Owen Michael Wilkins, Claire J. Fraser, Madolyn L. MacDonald, Shawn W. Polson, Zachary T. Herbert, Sridar V. Chittur, Andrew Hayden, Marcy L. Kuentzel, Michael E. Heinz, Gabriella Huerta, Holly S. Stevenson, Aditi Karmakar, Catrina C. Fronick, , Charles A. Whittaker

This study evaluates three cell preservation methods for scRNA-seq across multiple sites, showing concordant cell type results but platform-specific gene expression differences and better granulocyte retention with preservation methods.

Journal of Biomolecular Techniques JBT · Jun 8, 2026Peer-reviewedGenomics

Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells

Yasunari Seita, Keren Cheng, John Robert McCarrey, Nomesh Yadu, Ian H. Cheeseman, Alec Bagwell, Corinna N. Ross, Isamar Santana Toro, Li-hua Yen, Sean M. Vargas, Christopher S. Navara, Brian P. Hermann, Kotaro Sasaki

This study establishes methods to generate marmoset primordial germ cell-like cells from iPSCs, revealing a primate-specific germline transcriptional network and potential for in vitro gametogenesis modeling.

eLife · Jan 31, 2023Peer-reviewedDevelopmental Biology