Cancer BiologybioRxivPreprint
Delayed growth of Ewing sarcoma tumors associated with reduced expression and activity of Trk receptors, PI3K, and IGF1R
Bruna Almeida dos Santos, Natália Hogetop Freire, Lívia Fratini…·Caroline Brunetto de Farias
The paper shows that K252a treatment delays Ewing sarcoma tumor growth and reduces Trk, PI3K, and IGF1R expression and activity, with combined treatment more effective than single agents.
DOI 10.1101/2025.10.23.684233