Cancer BiologybioRxivPreprint
MYC shapes ER-mitochondria calcium transfer by directly targeting ITPR1: implications for MYC-induced safeguard mechanisms and cancer
Xingjie Ma, Athanasios Tsalikis, Mathieu Vernier…·David Bernard
This study shows MYC regulates ITPR1 to control ER-mitochondria calcium transfer, inducing cell death in normal cells but exploited by cancer cells for survival.
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