Jamie Galanaugh

This study identifies a striatal interneuron circuit that gates reinforcement by linking outcome processing to adaptive action selection through disinhibitory microcircuitry.

The paper identifies indirect pathway neurons in the tail of the striatum as critical for inhibitory control over sensory-driven behavior, showing their role in suppressing inappropriate actions and linking their dysfunction to neurodevelopmental disorders.

This study shows human glioblastoma cells integrate into brain-wide neuronal circuits, exhibit diverse connectivity, and respond to neuromodulatory inputs like acetylcholine, which promotes invasion and survival.

This paper develops a method using migratory cortical interneuron precursors to deliver therapeutic agents directly to glioblastoma, improving survival in mice.