Jonibek M. Muhsinov

This study identifies a striatal interneuron circuit that gates reinforcement by linking outcome processing to adaptive action selection through disinhibitory microcircuitry.

The paper identifies indirect pathway neurons in the tail of the striatum as critical for inhibitory control over sensory-driven behavior, showing their role in suppressing inappropriate actions and linking their dysfunction to neurodevelopmental disorders.

The paper creates a 3D atlas of SST, PV, and TH interneurons in the mouse caudoputamen, revealing distinct spatial distributions across striatal territories.