Author

Jie Chen

Fudan UniversityORCID 0000-0001-9375-7210Unclaimed ORCID profile · follow to get notified of new preprints

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Jie Chen15 papers · Nanjing Agricultural University

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:multiome· 1 Research Focus:protein structure prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bo YangiD· 1 shared D K Liu· 1 shared Hong Lu· 1 shared Jeffery D. MolkentiniD· 1 shared Jiuzhou HuoiD· 1 shared Lunqiang Zhao· 1 shared Ningxin GaoiD· 1 shared Qinghang MengiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Bo YangORCID

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2 papers

Recent·Most cited

A Transformer-based Multi-omics Model for Translation Efficiency in S. cerevisiae

D K Liu, Lunqiang Zhao, Wei Yushuo, Xirui Peng, Hong Lu, Xinhang Zhang, Jie Chen

TRIM predicts translation efficiency in S. cerevisiae using multi-omics data and a Transformer model, achieving high accuracy and biological interpretability.

bioRxiv · Jun 22, 2026 · PreprintMolecular Biology

AI-based Predictive Signaling Pathway Profiling in Cardiac Fibrosis Suggests a Novel Combinatorial Treatment Strategy

Bo Yang, Jie Chen, Qiongjie Mi, Jiuzhou Huo, Ningxin Gao, Xinhua Lin, Jeffery D. Molkentin, Qinghang Meng

The paper uses AI to analyze signaling pathways in cardiac fibrosis, identifying a dual-target treatment strategy with timed inhibition of JAK-STAT and TGF-β to reduce fibrosis without impairing acute scar formation.

bioRxiv · Dec 5, 2025 · PreprintCell Biology