Author

D K Liu

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Bioengineering· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:benchmarking· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:experimental assay· 2

Frequent Co-Authors

Abhay B. RamachandraiD· 2 shared Edward P. ManningiD· 2 shared Jack Di PaloiD· 2 shared Liqin LiniD· 2 shared Pramath DoddaballapuriD· 2 shared Xiting YaniD· 2 shared A. JustetiD· 1 shared Ahila Moorthy· 1 shared

Activity by Year

2026-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioengineering

Abhay B. RamachandraORCID

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Author profile →

5 papers

Recent·Most cited

A Transformer-based Multi-omics Model for Translation Efficiency in S. cerevisiae

D K Liu, Lunqiang Zhao, Wei Yushuo, Xirui Peng, Hong Lu, Xinhang Zhang, Jie Chen

TRIM predicts translation efficiency in S. cerevisiae using multi-omics data and a Transformer model, achieving high accuracy and biological interpretability.

bioRxiv · Jun 22, 2026 · PreprintMolecular Biology

Microstructural and Biomechanical Determinants of Biological Aging

Pramath Doddaballapur, Jack Di Palo, D K Liu, Liqin Lin, Cristina Cavinato, Abhay B. Ramachandra, Xiting Yan, Edward P. Manning

The paper develops a multimodal model to predict biological age using vascular microstructure and biomechanical parameters in mice, achieving high predictive accuracy.

bioRxiv · Jun 18, 2026 · PreprintBioengineering

A dish-to-biobank framework links β-cell nutrient-stress programs to genetic and dietary risk for Type 2 Diabetes

Xianming Wang, Hanbyul Lee, Ann Le, Berk Turhan, Nan Hu, Pretty S. Garcia, Xuewei Cao, D K Liu, Thahmina A. Ali, Nan Zhang, Breanna Williams, Caleb A. Lareau, G M Wang, Danwei Huangfu, Kushal K. Dey

bioRxiv · Jun 16, 2026 · PreprintGenetics

Biological Aging of the Cardiopulmonary System

D K Liu, Pramath Doddaballapur, Zhongyu Cai, Rira Choi, Jack Di Palo, Nicole M. Guerrera, Nebal Abu Hussein, Meredith S. Gwin, Liqin Lin, Siming Zheng, Yuening Zhang, A. Justet, Abhay B. Ramachandra, Xiting Yan, Edward P. Manning

This study quantifies biological cardiopulmonary aging in mice by integrating biomechanics and single-cell transcriptomics, revealing non-linear aging patterns and cell-type-specific gene expression changes.

bioRxiv · Jun 12, 2026 · PreprintPhysiology

Uncovering Pseudotime-Varying Genetic Causal Effects Along Single-Cell Trajectories for Pulmonary Disease Trait

Siyuan Chen, Ahila Moorthy, Paul Kwong Yu, Jingshu Wang, D K Liu

This study identifies pseudotime-dependent causal effects of genes on pulmonary fibrosis using scRNA-seq and GWAS data.

bioRxiv · Jun 10, 2026 · PreprintGenetics