Victoria R. Palzkill

This study shows that intramuscular adipose tissue (IMAT) accumulation worsens limb function in PAD/CLTI, and reducing IMAT improves muscle strength and work output in mice.

This study shows that blocking intramuscular adipose tissue (IMAT) formation after muscle injury improves muscle regeneration and function in mice.

This paper develops a 6-minute limb function test for preclinical hindlimb ischemia models to assess muscular performance and hemodynamics, showing it detects therapeutic differences better than traditional measures.

The paper uses single nuclei RNA sequencing to analyze muscle from PAD patients and controls, identifying transcriptional changes and cell type alterations associated with the disease.